click here -> p53 Workshop in Japan
Continue reading “Marco M Candeias & Rieko Ohki present the p53 Workshop in Japan at the ConBio2017 in Kobe”
The Molecular and RNA Cancer Unit
If you missed Marco’s talk or still have some questions, contact Marco to learn more about: “Cancer-specific mutations control the translation of p53 isoforms, leading to cancer cell survival and invasion”.
@ the speakers’ dinner
(left to right: Koji Itahana, Rieko Ohki, Sir David Lane, Marco M Candeias and Kanaga Sabapathy)
The Japan group.
Contact Rafaela to learn more about “p53 mutations influence IRES-dependent expression of p53 isoforms”
Contact Ana to learn more about “Characterization of an Internal Ribosome Entry Site (IRES) in p53 mRNA”
Continue reading “MaRCU in Prague at the 22nd Annual Meeting of the RNA Society”
Cherry trees by the river. Kyoto University in the back.
Up in the cold hills of Kyoto city, surrounded by snow, our bravest students challenged some of the most recent enigmas in biochemical research.
Continue reading “Biochemistry Class Seminar at Kansai Seminar House”
Read the complete recommendation at F1000.
Continue reading “Our EMBO Reports 2016 article recommended by Ronny Drapkin”
Wild‐type p53 functions as a tumour suppressor while mutant p53 functions as an oncogene. In this new study we propose that this switch depends on Δ160p53, the most conserved isoform of p53, which is overexpressed in p53 mutant cells.
Here is a video by leading author Marco explaining the importance of the findings:
Continue reading “Mutant p53 functions depend on truncated isoforms”