Output

molecular AND RNA CANCER UNIT

Our latest and greatest oral presentations, posters, and articles.
So much goodness all in one place!

under construction

2022

ARTICLES

Conserved double translation initiation site for Δ160p53 protein hints at isoform’s key role in mammalian physiology [IJMS]_MARCU

Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors [Nat. Commun.]

2021

ARTICLES

Long noncoding RNA-dependent methylation of nonhistone proteins [WIREs RNA] – review

PRESENTATIONS

Characterization of an oncogenic isoform of TP53: Δ160p53 (Catarina) – Poster

Full-length p53 mRNA is a frequent source of Δ133p53 and Δ160p53 protein isoforms (Maria) – Poster

Minip53, a new p53 isoform that responds to DNA damage in glioblastoma cell line (Shrutee) – Poster

2020

PRESENTATIONS

Shorter p53 isoforms: the new found link between cancer and p53 protein stabilization (Maria) – Poster

Accidental mini p53 isoform discovery could be key to elucidating new functions of p53 gene (Shrutee) – Poster

First insights on the regulation and function of the mammalian p53 isoform: Delta160p53 (Marco) – Oral

The Tumor Suppressor P53 Acquires Oncogenic Functions Due To A Translational Switch During Integrated Stress Response (Rafaela) – Oral

Regulation of IRES-mediated translation in p53 (Inês) – Poster

2019

ARTICLES

Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer [Adv. Exp. Med. Biol.]_marcu – review

PRESENTATIONS

Cancer mutations activate shorter p53 isoform through changes in mRNA function (Maria) – Poster

Δ160p53 isoform enhances tumorigenicity in lung cancer cell line (Lina) – Poster

Translational switch during integrated stress response (ISR) provides oncogenic capability to tumor suppressor p53 (Marco) – Oral

RNA structure-function analysis of regulatory regions of p53 mRNA (Bruna) – Poster

Cap-independent translation and cancer (Luísa) – Oral

2018

PRESENTATIONS

Common p53 mutations induce IRES-mediated translation of oncogenic shorter p53 isoforms (Bruna) – Oral

2017

ARTICLES

Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition [RNA]_{RNA metabolism}

New functions of p53 mRNA and p53 isoforms [Experimental Medicine]_marcu – review

PRESENTATIONS

2016

ARTICLES

Cancer-specific mutations in p53 induce the translation of delta160p53 promoting tumorigenesis [EMBO Rep.]_marcu

PRESENTATIONS

2015

ARTICLES

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin [elife]

PRESENTATIONS

2014

ARTICLES

HDMX Folds the Nascent p53 mRNA
following Activation by the ATM Kinase [Mol. Cell]_marcu

PRESENTATIONS

2013

PRESENTATIONS

2012

ARTICLES

The p53 mRNA-Mdm2 Interaction Controls Mdm2
Nuclear Trafficking and Is Required for p53
Activation following DNA Damage [Cancer cell]_marco

Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells

PRESENTATIONS

2011

ARTICLES

The can and can’t dos of p53 RNA [biochimie]_marcu – review

PRESENTATIONS

2010

ARTICLES

Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47 [mol. cell]_marcu

Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes

PRESENTATIONS

Marco before MarCU

2009

p53 and little brother p53/47: linking IRES activities with protein functions – review

The p53 mRNA-Mdm2 interaction

2008

p53 mRNA controls p53 activity by managing Mdm2 functions [Nat. Cell Biol.]_marco

Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47

The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin

Gly-Ala Repeats Induce Position- and Substrate-specific Regulation of 26 S Proteasome-dependent Partial Processing

2006

Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation [oncogene]_marco

%d bloggers like this: